Evaluation of homoeopathic medicines as add-on to institutional management protocol in Acute Encephalitis Syndrome: An exploratory observational comparative study

Authors

Raj Manchanda, Director General, Central Council for Research in Homoeopathy, New Delhi
Praveen Oberai, Research Officer/Scientist-4, Central Council for Research in Homoeopathy, New Delhi
Varanasi Roja, Research Officer/Scientist-1, Central Council for Research in Homoeopathy, New Delhi
Supriya Singh, Senior Research Fellow (H), Clinical Trial Unit (Homoeopathy), Gorakhpur, Uttar Pradesh
Neha Singh, Senior Research Fellow (H), Clinical Trial Unit (Homoeopathy), Gorakhpur, Uttar Pradesh
Tariq Khan, Senior Research Fellow (H), Clinical Trial Unit (Homoeopathy), Gorakhpur, Uttar Pradesh
Ramesh Prasad, Research Officer/Scientist-1, Clinical Trial Unit (Homoeopathy), Gorakhpur, Uttar Pradesh
J Singh, Research Officer/Scientist-4, Clinical Trial Unit (Homoeopathy), Gorakhpur, Uttar Pradesh

Keywords

Acute Encephalitis Syndrome, Homoeopathy, India, Institutional management protocol, Morbidity, Mortality, Observational study

Article Type

Original Article

Abstract

Background: Acute Encephalitis Syndrome (AES) treated according to Institutional Management Protocol (IMP) has considerable mortality and morbidity. The study was undertaken to evaluate the effect of homoeopathic treatment (H) as an add-on to IMP (IMP + H) for children affected with AES. Materials and Methods: This was an exploratory observational study carried out in the IPD setting (epidemic ward) of Baba Rhaghav Das Medical College and Nehru Hospital, Uttar Pradesh (July to November 2012) using convenience sampling. Children whose guardians gave consent were treated with IMP + H and rest remained on IMP only. Glasgow outcome scale was used at discharge for the final outcome. Results: 151 children (121 in IMP + H and 30 in only IMP) diagnosed with AES (aged 6 months to 18 years) were enrolled. The results showed 12 (9.9%) death out of 121 children administered IMP + H whereas it was 13 (43%) out of 30 children on IMP alone. Proportional odds analysis with covariate adjustment showed added benefit of Homoeopathy in children with AES as compared to IMP alone (adjusted odds ratio, 0.17, 95% confidence interval 0·06-0.45, P = 0·0001). The most useful medicines are Belladonna, Stramonium, Arsenicum album, Helleborus, Bryonia alba, Sulphur, and Cuprum metallicum. Conclusion: This exploratory observational study suggests reduction of mortality and morbidity with add-on homoeopathic medicine. Further randomized controlled trial study with comparable groups is desirable. If findings are confirmed by subsequent research, add-on Homoeopathy might have relevant implication for its management.

Digital Object Identifier

10.4103/0974-7168.154347

Publisher

Wolters Kluwer India Pvt. Ltd.

How to cite this article

Manchanda R, Oberai P, Roja V, et al. Evaluation of homoeopathic medicines as add-on to institutional management protocol in Acute Encephalitis Syndrome: An exploratory observational comparative study. Indian J Res Homoeopathy 2015;9:34-41. doi: 10.4103/0974-7168.154347