Indian Journal of Research in Homoeopathy
Keywords
Tribulus terrestris, Homoeopathic potencies, Biochemical and Haematological profiles, Albino rats.
Article Type
Original Article
Abstract
Although in Homoeopathy different potencies of Tribulus terrestris (Ikshugandha) have been commonly prescribed in urinary affections, especially dysuria and in debilitated status of the sexual organs, no scientific experimental data has been documented to establish their safe use. The present study was, therefore, undertaken to generate preliminary data on the biochemical and haematological parameters with homoeopathic drug Tribulus terrestris. The four potencies (3x, 6x, 12x and 30c) of this drug were administered orally in daily doses of 0.1ml, 0.2ml and 0.5ml/rat for 14 days and their effects on biochemica/ and haematological parameters were studied on 21" and 28" day during post-treatment period. Preliminary findings on biochemical (serum glucose, serum total cholesterol, serum triglycerides, serum total protein, serum albumin, serum urea and SGOT and SGPT levels) and haemotological (haemaglobin content, total R.B.C. and total W.B.C. and differential leucocyte counts) parameters showed variable effects of different potencies of T. terrestris, but all the observed values for both biochemical and haematological profiles were found to be within the normal range of healthy animals. There was no apparent effect on the behaviour of animals during the period of study. This homoeopathic drug did not have any toxic effect in the four potencies studied. However, in order to arrive definite conclusion on the complete safety profiles of this drug, further research on acute and chronic toxicity studies are needed in different species of experimental animals.
Digital Object Identifier
10.53945/2320-7094.2265
Publisher
Central Council for Research in Homoeopathy
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 International License.
How to cite this article
Sundaram EN, Singh KP, Reddy PM, Nair KR, Nayak C. Biochemical and haematological evaluation of homoeopathic drug Tribulus terrestris in rats. Indian J Res Homoeopathy 2009;3:44-53. doi: 10.53945/2320-7094.2265
